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MD Formulated
Dr. P. Alexander Ataii, MD
Board-Certified · Laser Clinique San Diego · 20+ years
"I built this serum around encapsulated retinol so patients get real anti-aging results, smoother lines and clearer skin, with far less of the irritation that scares people away from retinol."
What's Inside
Product Details
A lightweight, encapsulated retinol serum formulated by Dr. P. Alexander Ataii based on 20+ years of treating fine lines, acne, and uneven texture at Laser Clinique San Diego.
Size
50 ml / 1.7 fl oz · Airless pump bottle
Skin Concern
Fine lines, wrinkles, acne, scarring & uneven texture
Free From
Parabens · Sulfates · Artificial Fragrance · Mineral Oil
Made In
USA · FDA-Registered · Cruelty-Free
The Story Behind the Formula
From the Clinic to Your Home
Dr. P. Alexander Ataii built Ataii Aesthetic MD on a single premise: the same clinical-grade formulas that deliver results in his San Diego med spa should be accessible to everyone: not just those who can afford in-clinic treatments.
His father was a pioneering pharmacist and chemist who developed regenerative skincare formulas in the 1960s, work that earned international recognition and helped a Hollywood actress restore her complexion. Dr. Ataii refined and modernized that legacy through two decades of clinical practice.
This Renew Retinol is the anti-aging serum Dr. Ataii reaches for at Laser Clinique San Diego for patients who want smoother, clearer skin, an encapsulated retinol his patients take home to soften fine lines, refine texture, and calm breakouts without the usual retinol irritation.
Top Doctor · Multiple Years
Patient's Choice Award
On-Time Doctor
Most Compassionate
America's Best Physicians
As Featured In
Application Guide
How to Use
A simple evening ritual for smoother, renewed skin.
Cleanse
Clean, Dry Skin
Cleanse and pat dry before bed so skin is ready.
→
Apply
Pea-Sized Amount
At night, smooth a thin layer over the face, avoiding the eye area.
→
Layer
Soothing Moisturizer
Follow with moisturizer to buffer and lock in hydration.
→
Protect
SPF Every Morning
Always wear SPF the next day, since retinol increases sun sensitivity.
For best results, use consistently for at least 4 to 8 weeks to see smoother texture, softer fine lines, and clearer skin.
Get The Most From It
Retinol Ramp-Up Protocol
A simple protocol to build retinol tolerance and renew your skin over the weeks ahead.
1
Week 1
Start 2 to 3 nights
Apply on clean, dry skin so your skin adjusts comfortably.
2
Weeks 2 to 4
Build to every other night
Increase frequency as tolerated, always finishing AM with SPF.
3
If Irritation
Buffer with moisturizer
Apply moisturizer before or after retinol to ease any dryness.
4
Long-Term
Use nightly as tolerated
Renewal is cumulative, the smoothest results build over time.
Pro tip from Dr. Ataii:Daily SPF is non-negotiable with retinol. It increases sun sensitivity, and protection keeps your results from reversing.
Full Synergy
Encapsulated Renewal Complex
Encapsulated retinol paired with calming, hydrating actives, delivering smoother, renewed skin with far less of the irritation retinol is known for.
Encapsulated Retinol
Smooths & Renews
Time-released retinol accelerates cell turnover to soften fine lines and refine texture, encapsulated for gradual, gentler delivery.
Niacinamide
Calms & Evens
Vitamin B3 strengthens the barrier and helps even tone, reducing the redness and dryness retinol can trigger.
Hyaluronic Acid
Hydrates
Draws moisture deep into the skin to keep it plump and comfortable while retinol does its work.
Vitamin E
Antioxidant Defense
A nourishing antioxidant that conditions skin and helps protect against environmental stress.
Shea Butter
Soothes & Softens
Rich, replenishing butter that cushions the skin and buffers retinol for a smooth, supple finish.
20+
Years Clinical Experience
4.9 ★
Average Review Score
5
Clinical Renewal Actives
30
Day Money-Back Guarantee
Why It Works
Renew, Without the Irritation.
Most retinols force you to choose between results and comfort. This Renew Retinol uses encapsulated, time-released retinol buffered with calming, hydrating actives, so skin renews smoothly with far less irritation.
Encapsulated retinol releases gradually to smooth lines with less irritation
Niacinamide calms redness and supports the skin barrier
Hyaluronic acid keeps skin hydrated and plump throughout renewal
Vitamin E adds antioxidant defense against environmental stress
Shea butter cushions and softens for a comfortable finish
Real Patients. Real Results.
What Our Customers Say
★★★★★
"My fine lines around my eyes and forehead have softened so much. And it never stung or peeled like other retinols I have tried."
Bahar B.
✓ Verified Buyer
★★★★★
"I was nervous about retinol because my skin is sensitive, but this one is gentle. My texture is smoother and my breakouts have calmed down."
Christine
✓ Verified Buyer
★★★★★
"A few weeks in and my skin looks fresher and more even. Old acne marks are fading and everything feels softer."
Alyssa N.
✓ Verified Buyer
★★★★★
"This absorbs fast and my skin looks renewed in the morning. The encapsulated formula really is easier on my skin."
Alicia
✓ Verified Buyer
Common Questions
Frequently Asked
Use it in the evening on clean, dry skin. If you are new to retinol, start 2 to 3 nights a week for the first couple of weeks, then build to every other night or nightly as your skin adjusts. Always wear SPF the next morning.
Yes. The retinol is encapsulated for slow, gentler release, and it is buffered with niacinamide, hyaluronic acid, and shea to limit irritation. If your skin is reactive, start slowly, a few nights a week, and apply moisturizer before or after to ease any dryness.
Yes. It layers well with hydrating serums, gentle moisturizers, and SPF. Because retinol is a strong active, avoid combining it with other exfoliating acids or additional retinoids on the same night. Apply this serum at night, then follow with moisturizer.
Renewal is gradual. Many people notice smoother, fresher-looking skin within the first couple of weeks, while softer fine lines, refined texture, and clearer skin typically become visible after 4 to 8 weeks of consistent use. Results build over time.
We recommend using Renew Retinol at night. Retinol can make skin more sensitive to sunlight, so applying it in the evening and wearing SPF during the day gives you the best, most comfortable results.
Yes, with care. Use Vitamin C or exfoliating acids in your morning routine and reserve this retinol for the evening. Keeping strong actives on separate parts of the day helps you get the benefits without over-stressing your skin.
We stand behind every product with a 30-day money-back guarantee. If you are not completely satisfied, contact our team and we will make it right.
We recommend speaking to your OBGYN and avoiding any products that may contain Retinol or skin lighteners. We have categorized which products are safe for which skin types on our page. If you have any questions please contact us at Ataii Aesthetic MD.
If you have dry skin, we recommend applying a Soothing Moisturizer after Renew Retinol.
Our products have been developed to target specific skin concerns such as dry, oily, acne prone, sensitive, and uneven skin types. You can find product for your specific skin concern here: Acne, Aging Skin, Dry Skin, Normal Skin, Oily Skin, Pigmentation, Rosacea and Sensitive Skin.
We recommend speaking or consulting with your doctor before using any new skincare product. If you have any questions please contact us at Ataii Aesthetic MD.
All our products are manufactured in USA.
All our products are paraben-free, BPA-free and triclosan-free.
We are proud to share that all our products are 100% cruelty-free. This means that none of our products have been tested on animals. We are committed to creating high-quality products while upholding ethical practices that protect animal welfare.
All product descriptions are available on each bottle as well as on each product page.
Store all Ataii Aesthetic MD skincare products at room-temperature, away from direct sunlight. Do not leave products in hot environments such as inside of a hot car, as this can degrade the products and make them ineffective.
As Seen On Television
Dr. Ataii in the News
A trusted voice in skincare, Dr. P. Alexander Ataii is regularly invited to share his expertise on local television, breaking down what actually works for healthy, resilient skin.
